News and Research
Immune System
Study Shows Low Risk Of Vaccinia Transfer After Smallpox
Immunization
2-2-2004
The threat of bioterrorism has led to the recommendation
to vaccinate health care workers and other first responders,
but some worry about the side effects of smallpox vaccination,
which can harm children, pregnant women and people with
immune disorders or certain skin conditions. According to
an article published in the February 15 issue of Clinical
Infectious Diseases, now available online, people vaccinated
against smallpox pose a low risk of accidentally inoculating
others if they follow proper bandaging and hand-washing
procedures.
Smallpox
vaccinations leave an open wound on the upper arm containing
a live virus that could infect others. If a child, a person
with eczema or someone with an immune disorder is infected,
the virus can cause serious health problems or death. Consequently,
some hospitals decided that health care workers should not
be vaccinated against smallpox to prevent accidental transmission
of the virus to vulnerable patients.
"Hopefully,
this study has helped reassure individuals about the transmission
of smallpox," says lead author Thomas Talbot, MD, of
Vanderbilt University Medical Center. The risk of transmission
is vastly reduced if those vaccinated against smallpox keep
the vaccine site bandaged and practice "good, thorough
hand-washing with soap and water or an alcohol-based product"
after changing the bandage, says Dr. Talbot.
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Dr.
Talbot sees no need for everyone to get vaccinated against smallpox,
because civilian and military vaccination campaigns have created
a safety net of sorts. "If someone were to intentionally
release smallpox, we have our first wave of health care responders
protected," he says. The vaccine can be administered as long
as three to four days after exposure, so health care workers who
have been vaccinated could "take care of patients and vaccinate
everybody else" in the days following an attack, says Dr.
Talbot.
Whether
hospitals will change policies regarding vaccinations for health
care workers based on the study's outcome remains to be seen.
"It's been an interesting question, and hopefully now we've
got a lot of contemporary data to help answer it," says Dr.
Talbot.
Founded in 1979, Clinical Infectious Diseases publishes
clinical articles twice monthly in a variety of areas of infectious
disease, and is one of the most highly regarded journals in this specialty.
It is published under the auspices of the Infectious Diseases Society
of America (IDSA), based in Alexandria, Va., a professional society
representing more than 7,500 physicians and scientists who specialize
in infectious diseases.
This article has been adapted from a news release
issued by Infectious Diseases Society Of America, www.idsociety.org.
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